Though there is still no comprehensive cure for cystic fibrosis, the treatment and management options have drastically improved the prognosis for people with cystic fibrosis, enabling them to lead long and full lives. CF principally affects the secretions in the body, thus affecting many different organs with mucus buildup. It is of the utmost importance that people with cystic fibrosis maintain a strict medication and treatment schedule to increase longevity.
Cystic fibrosis isn’t curable yet, but there are many drug options that have drastically improved quality and longevity of life span. CF affects many different organs and there are many treatment options for these symptoms.
Cystic Fibrosis Antibiotic Medications
Pseudomonas aeruginosa is an opportunistic bacterial infection that commonly presents itself in the lungs of people with cystic fibrosis due to mucus buildup. Consistent and effective treatment of this infection is integral to the longevity of patients with cystic fibrosis. We outline five of the most common medications used to treat Pseudomonas aeruginosa.
CaystonⓇ is an inhaled form of an antibiotic (aztreonam) that is used to treat the lung infections associated with cystic fibrosis. It was specifically designed to treat pseudomonas aeruginosa.
TOBIⓇ is an inhaled form of tobramycin, an antibiotic used to treat opportunistic lung infections in cystic fibrosis. It is commonly administered portably via handheld PARI LC PLUS reusable nebulizer.
The Kitabis PakⓇ includes kitabis, a tobramycin solution that is specifically formulated for inhaled delivery by hand-held nebulizer (PARI LC PLUS), also included in the Kitabis PakⓇ.
BethkisⓇ is another tobramycin solution that is designed for delivery using a PARI LC PLUS nebulizer. Treatments last about 15 minutes and it is taken in cycles of 28 days on and 28 days off.
CIPROⓇ, ciprofloxacin, is an oral antibiotic. Unlike tobramycin, ciprofloxacin does pass the gastrointestinal tract and affects the body in multiple systems. It works by killing and inhibiting the growth of bacteria throughout the body.
Disclaimer: Above are some prescriptions that may be taken to improve lung function and fight off infections. It does not include all medications available. We are not giving you medical advice. Please consult your doctor for further information and prescriptions.
Airway Clearing Medications
Pulmozyme is a mucolytic that removes genetic information that causes mucus to be excessively sticky. This enables the body to clear the mucus build up from the airways.
Acetylcysteine, or N-acetylcysteine (NAC),is also a mucolytic that is administered by inhalation rather than orally. It works by splitting disulfide bonds that link proteins in the mucus, making it easier to expectorate. The medication also creates the helpful antioxidant glutathione (GSH), boosting the immune system. It also has anti-inflammatory properties.
NOTE: Acetylcysteine is not approved to treat CF, but is prescribed for its off-label benefits.
The most common enzyme treatment for cystic fibrosis is pancrelipase, brand name Creon, Pancreaze, etc. Since cystic fibrosis causes mucus build up in the ducts from the pancreas, the enzymes that are necessary for proper digestion never reach the digestive tract. This creates the need for supplementation of pancreatic enzymes to promote the proper absorption of vitamins and minerals.
Do you have questions about CF Treatment Options?
If you have any questions regarding CF treatment options, IV Solutions has on-call pharmacists, provides 24-7 patient support, and reimbursement assistance. For more information, call 1-800-658-6046.
Drugs and Supplements Ciprofloxacin. Mayo Clinic. Sept. 1, 2015Accessed Sept 9, 2015
Kitabis PakⓇ Cystic Fibrosis. IV Solutions. June 24, 2015. Accessed Sept 9, 2015
TOBIⓇ Cystic Fibrosis. IV Solutions. June 30, 2015. Accessed Sept 9, 2015
BETHKISⓇ Tobramycin Inhalation Solution. IV Solutions. Oct 15, 2012. Accessed Sept 9, 2015
Mucolytics. Cystic Fibrosis Foundation. July 21. 2015. Accessed Sept 9, 2015
Enzyme Replacement Therapy for Cystic Fibrosis. WebMD. Sept 9, 2014. Accessed Sept 9, 2015